Medically reviewed by Dr. Sarah Agha, General Practitioner, Diva Clinic Dubai
Last reviewed:

Quick Answer

  • Typical duration: 3 to 4 months
  • First effect: 3 to 5 days after treatment
  • Full effect: Around 2 weeks
  • First-time patients: Results often fade sooner
  • Repeat treatments: Usually every 3 to 4 months
  • Jaw treatment: Often lasts 4 to 6 months

How Long Do Anti-Wrinkle Injections Last?

Anti-wrinkle injections usually last 3 to 4 months. The botulinum toxin relaxes the treated muscle. Your nerves then grow new connections to the muscle, and movement returns gradually.

What Does the Timeline Look Like?

Time After TreatmentWhat to Expect
Day 1 to 2No visible change. Small bumps at injection points settle within an hour.
Day 3 to 5Muscle movement starts to soften
Week 2Full effect. Review appointment for any adjustment.
Month 2 to 3Results hold steady
Month 3 to 4Movement returns gradually. Lines start to reappear.

How Long Do Results Last by Area?

AreaTypical Duration
Forehead lines3 to 4 months
Frown lines between the brows3 to 4 months
Crow’s feet3 to 4 months
Jaw muscle for clenching or slimming4 to 6 months
Underarm sweating6 months or longer

What Affects How Long Results Last?

How Often Should You Repeat Treatment?

Most people repeat treatment every 3 to 4 months. Doctors avoid top-ups sooner than 12 weeks apart. Short gaps raise the chance of your body forming antibodies to the toxin, which reduces the effect over time.

What Aftercare Helps Results?

Frequently Asked Questions

Why did my anti-wrinkle injections wear off after 2 months?

Strong muscles, a low dose or a fast metabolism shorten results. Your doctor adjusts the dose at your next treatment.

Do wrinkles get worse after anti-wrinkle injections wear off?

No. Lines return to their earlier state. Regular treatment often softens lines over time.

Do anti-wrinkle injections last longer with repeat treatment?

Often yes. Muscles used less over time weaken, so results often last longer.

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This article is for general educational purposes and does not replace a personalised consultation with a licensed medical aesthetics provider. Individual results vary.